DATE CHANGE - October 6-9, 2022 - IWWM-12 Madrid, Spain
Dear Colleagues:
I am writing to you with great sorrow as we watch the coronavirus epidemic continue to impact lives across the globe. Over 500,000 of our fellow human beings have lost their lives to COVID-19, as both the death toll and number of coronavirus cases continues to grow. Here in the United States, the coronavirus cases have greatly increased with much strain on the medical system for many of our states. In addition, there have been many travel restrictions imposed for travel to/from the United States, and many other countries around the globe in response to the COVID-19 pandemic. Our recognition at this time is that it will not be possible to hold the IWWM-11 this year given the large safety concerns and travel restrictions.
Our initial intent was to move the workshop planned for this October in Madrid to 2022. We have succeeded in making this adjustment and have re-booked the WM workshop for the Westin Madrid for October 6-9, 2022. Our website has been adjusted to reflect this postponement. Our local chairs, Professors Ramon Garcia-Sanz and Jesus San Miguel have been very supportive of this adjustment, and we look forward to working with them on the program and being in Madrid as IWWM-12 in 2022.
We are also giving consideration at this time for a smaller WM workshop (IWWM-11) to be held next summer in Boston. This workshop would permit a smaller group of 40 persons to safely attend to discuss emerging data for WM and help in the development of WM treatment guidelines. While we thought this might have been possible for this Fall, the new realities of the COVID-19 crisis, and the feedback from many of our scientific advisors favored a live, but smaller meeting next year.
We will inform you of the details of the revised workshops once they become available. We thank you for all hard work and efforts on behalf of WM patients.
Steve Treon MD, PhD
Chair
WM Workshop Organizing Committee
Read more: DATE CHANGE - October 6-9, 2022 - IWWM-12 Madrid, Spain
Waldenstrom's Macroglobulinemia Clinic
The Waldenstrom's Macroglobulinemia Clinic at the DFCI is devoted to the care of patients with Waldenstrom's Macroglobulinemia and related IgM disorders, including IgM MGUS, Myeloma and Neuropathies.
For more information on the WM Clinic at DFCI, please visit the DFCI Center for Hematologic-Oncology/Waldenstrom's Macroglobulinemia Clinic.
Basic Research
Waldenström’s macroglobulinemia (WM) is a distinct B-cell malignancythat results from the accumulation, predominantly in the bone marrow, of clonally related B type lymphocytes, lymphoplasmacytic cells and plasma cells which secrete a monoclonal IgM protein.1 This condition is considered to correspond to the lymphoplasmacytic lymphoma (LPL) as defined by the World Health Organization classification system.2 Most cases of LPL are WM, with less than 5% of cases made up of IgA, IgG and non-secreting LPL ...
Latest Bing Center News
Ibrutinib Demonstrates Long-Term Safety, Activity in Relapsed/Refractory WM
Ibrutinib is a highly active and tolerable therapy for symptomatic, relapsed, or refractory patients with Waldenström macroglobulinemia (WM) and a preferable option for use in previously treated patients, according to a study published in the Journal of Clinical Oncology (2020;JCO2000555. doi:10.1200/JCO.20.00555).
The fourth issue of the 21st volume of the IWMF Torch is now online!
If you’ve ever had questions about clinical trials, this issue will help clarify various aspects of them, from both the doctor’s and the patient’s perspectives. It will be obvious that medical as well as personal reasons need to be considered before making the plunge.
BTK Inhibitors Transform Waldenström Macroglobulinemia Management
BTK inhibitors have transformed the treatment of patients with Waldenström macroglobulinemi; with 4 agents under examination in the space, selection will depend on availability, toxicity, convenience, and cost.
IWMF Renews Funding for Pivotal WM Research Project with Dr. Steve Treon
The International Waldenstrom's Macroglobulinemia Foundation (IWMF) Board of Trustees has reviewed and approved funding an additional $500,000 to renew Dr. Steve Treon's legacy research project.
Making Sense of the Science of WM with Dr. Zachary Hunter
Making Sense of the Science of WM sets out a framework for patients to understand the basic genetic concepts behind the mutations that are important in WM, to appreciate the ways in which these mutations impact the signaling systems that control the behavior of WM cells, and to recognize how these mutations are changing the landscape of therapies for WM.
Steven P. Treon, MD, PhD, on Treating COVID-19–Related Pulmonary Failure by Targeting BTK With Ibrutinib
Steven P. Treon, MD, PhD, of Dana-Farber Cancer Institute, discusses Bruton’s tyrosine kinase (BTK), which is activated during severe COVID-19 infection. Patients with the coronavirus and chronic lymphocytic leukemia who remained on the BTK inhibitor ibrutinib had a mild disease course, with decreased C-reactive protein and improved oxygenation. Clinical trials to validate the role of BTK inhibitors in treating COVID-19–related pulmonary distress are now underway.
Next Generation BTK-Inhibitors in Waldenstrom's Macroglobulinemia
Dr. Steven Treon delivered this on-line lecture on August 5, 2020 for the benefit of the WMFC Toronto Support Group. It is our privilige to share it with the entire WM community. It focuses on the role of BTK Inhibitors in the treatment of Waldenstrom's Macroglobulinemia, and the advances being made based on the latest research.
2020 IWMF GLOBAL EDUCATIONAL WEBINAR: Getting to Know WM: Basics & Beyond with Dr. Jeffrey Matous
The International Waldenstrom's Macroglobulinemia Foundation invites you to join us for the first installment in our 2020 IWMF Global Educational Webinar series.
Waldenstrom Patient Stories: Finding Strength
When Peter DeNardis was diagnosed with Waldenstrom macroglobulinema (WM) 17 years ago, all he knew was that he had an incurable cancer. He had never heard of this rare type of non-Hodgkin lymphoma. A married father of three in his early 40s, DeNardis worried about how his illness would impact his family. How would his passing affect them emotionally and financially?
Consensus Statement on the Management of Waldenström Macroglobulinemia Patients During the COVID-19 Pandemic
In the light of the COVID-19 pandemic, the International Workshop on Waldenström Macroglobulinemia (IWWM) Treatment Recommendations Panel felt the need to provide a consensus statement for the management of Waldenström Macroglobulinemia (WM) patients during this challenging time.