Bone marrow involvement and subclonal diversity impairs detection of mutated CXCR4 by diagnostic next-generation sequencing in Waldenstr€om macroglobulinaemia

Joshua N. Gustine, Lian Xu, Guang Yang, Xia Liu, Amanda Kofides, Nicholas Tsakmaklis, Manit Munshi, Maria Demos, Maria L. Guerrera, Kirsten Meid, Christopher J. Patterson, Shayna Sarosiek, Andrew R. Branagan, Zachary R. Hunter, Jorge J. Castillo1, and Steven P. Treon

Bone marrow involvement and subclonal diversity impairs detection of mutated CXCR4 by diagnostic next-generation sequencing in Waldenstr€om macroglobulinaemia

2021 British Society for Haematology Received 22 December 2020; accepted for publication 9 February 2021 doi: 10.1111/bjh.17385