Ascentage Pharma (6855.HK), a globally focused, clinical-stage biotechnology company engaged in developing novel therapies for cancers, chronic hepatitis B (CHB), and age-related diseases, today announced that the US Food and Drug Administration (FDA) has granted APG-2575, a novel Bcl-2 inhibitor being developed by the company, an Orphan Drug Designation (ODD) for the treatment of Waldenström macroglobulinemia (WM).

This is the first ODD granted to APG-2575, and the second ODD Ascentage Pharma received from the FDA, following the previous ODD granted to the company's third-generation BCR-ABL inhibitor HQP1351 in May 2020 for the treatment of chronic myeloid leukemia.

For more info, please visit:


For info on clinical trials involving this drug, please visit: