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A message from Dr. Steven Treon, MD, Ph.D: I would like to share with you and the IWMF membership the paper which was just published in BLOOD as a FIRST EDITION. It describes the course of 6 WM patients on ibrutinib who contracted COVID-19.

Please feel free to share with the membership. We are beginning two prospective multicenter trials in COVID-19 patients, one with ibrutinib and the other with zanubrutinib. Much of what we have learned about the Toll-receptor/MYD88 pathway in WM enabled us to re-purpose much of this knowledge to COVID-19 that exploits this pathway for producing lung injury. The IWMF enabled much of this learning, and we are grateful that the findings from those studies could be re-purposed against COVID-19.

Click here to view the article: 

https://ashpublications.org/blood/article/doi/10.1182/blood.2020006288/454437/The-BTK-inhibitor-ibrutinib-may-protect-against

Click here to download the publication (PDF)