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Phone: 617-632-2681
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Dr. Steven Treon is the Director of the Bing Center for Waldenström's Macroglobulinemia and an Attending Physician for the Department of Medical Oncology at the Dana-Farber Cancer Institute and Brigham and Women’s Hospital in Boston, Massachusetts. He is also a Professor of Medicine at Harvard Medical School in Boston, and is the Chair of the Waldenström's Macroglobulinemia Clinical Trials Group.

Dr. Treon received a medical degree with honors from the Boston University School of Medicine, and a master’s degree in biochemistry and a doctorate of philosophy in tumor immunology from the graduate school at Boston University Medical Center. Dr Treon completed an internship and residency in internal medicine at Boston University Medical Center. He also completed a clinical fellowship in hematology and oncology at the Massachusetts General Hospital and a research fellowship at the Dana-Farber Cancer Institute and Harvard Medical School. He received certification from the American Board of Internal Medicine (ABIM) in Internal Medicine and Medical Oncology, and continues to maintain his ABIM certification in Medical Oncology.

Dr. Treon’s research interests are focused on understanding the genetic basis and pathogenesis of Waldenström’s Macroglobulinemia (WM), and the development of targeted therapeutics for this malignancy. Using whole genome sequencing, the Treon laboratory discovered the highly prevalent MYD88 L265P and CXCR4 WHIM mutations in WM, permitting the development of diagnostic molecular testing and targeted treatments for WM. Signaling work performed in the Treon laboratory established the critical role of Bruton’s Tyrosine Kinase (BTK) as a key mediator of MYD88 signaling in WM cells. This discovery enabled the first ever breakthrough designation by the U.S. FDA for the accelerated approval of the BTK inhibitor ibrutinib for the treatment of WM. Dr. Treon served as the principal investigator of the pivotal trial that supported the regulatory approval of ibrutinib by the U.S. FDA and European Medicines Agency for the treatment of WM. He has also been the principal investigator for other clinical trials that resulted in the adoption of many novel therapeutics and combination therapies for the treatment of WM.

Dr. Treon has published over 250 original articles, reviews, reports, and book chapters that have appeared in many high impact journals and text books. He has been a keynote speaker and lecturer on the genomic basis, pathogenesis, clinical features, and treatment of WM at prestigious national congresses, international conferences, hospital grand rounds, tumor boards, regional medical society conferences, workshops, and patient meetings. He is a member of the American Society of Hematology, American Society of Clinical Oncology, American Association for Cancer Research, European Society of Hematology, and the British Society of Hematology, and has given “Meet the Professor”, Educational Session, as well as presentations on original research at the annual meetings of these associations. Dr. Treon is also the principal organizer of the International Workshops on WM which have served as the principal forum for the exchange of novel scientific and clinical data on WM. He has been a mentor to physicians and scientists at the Bing Center for WM, and is also a regular lecturer at Harvard Medical School and its affiliated hospitals where he teaches medical students, interns, residents and fellows on the topic of plasma cell malignancies.

For his clinical and research efforts, Dr. Treon has received awards from various organizations including an ASCO Young Investigator Award, the Robert A. Kyle Award, the Jan Gosta Waldenstrom Lifetime Achievement Award, the Laurie Strauss Leukemia Society Outstanding Cancer Investigator Award, designation as “America’s Top Doctor” by U.S. News and World Report, and the “One-Hundred Award” from the Massachusetts General Hospital. In 2011, and 2013, Dr. Treon’s research work received “Best of ASH” designations at the Annual Meeting of the American Society of Hematology.

 

Dr. Treon is listed by US News and World Report as one of its Top Docs. Dr. Treon iis listed in the top 1% of doctors in his specialty. Please click on the icon to go to the US News & World Report web page for Dr. Treon.

Latest Bing Center News

Latest News in the Treatment of WM - TELECONFERENCE 3/19/2020

Latest News in the Treatment of WM - TELECONFERENCE 3/19/2020

CancerCare, in association with the IWMF, is holding a Teleconference titled –  The Latest News in the Treatment of Waldenstrom’s Macroglobulinemia on Thursday, March 19th  from 1:10-2:30  pm Eastern Time (ET). Presenting will be Steven Treon, MD, Ph.D, Christian Buske, MD, Carolyn Messner, DSW, OSW-C, FAPOS, FAOSW, and Carl Harrington (IWMF).

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25th Annual IWMF Educational Forum

25th Annual IWMF Educational Forum

25th Annual IWMF Educational ForumJune 5-7, 2020Renton, WA"2020 Vision: A World Without WM"

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Steven Treon, MD, PhD to serve as advisor to IWMF Board

Steven Treon, MD, PhD to serve as advisor to IWMF Board

Dr. Steven Treon, MD, PhD, (Dana-Farber Cancer Institute) has agreed to advise the IWMF Board of Trustees. Dr. Treon joins Dr. Ansell of the Mayo Clinic in providing the critical perspective of world-renowned clinicians/researchers to the IWMF Board. Dr. Treon and Dr. Ansell also will jointly co-chair the IWMF Scientific Advisory Committee.

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Florida Blood Cancer Conference 2020 (LLS)

Florida Blood Cancer Conference 2020 (LLS)

Dr. Steven Treon will be lecturing at the upcoming Blood Cancer Conference (BCC), one of many programs developed by The Leukemia & Lymphoma Society (LLS) to meet the needs of patients, survivors, families and oncology professionals, the people who deal with blood cancer every day and the people who care for them. BCC attendees receive the most current information and access to local resources to help navigate and make informed decisions about their treatment and survivorship.

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ASH 2019 - Bing Center Presentations

ASH 2019 - Bing Center Presentations

The ASH 2019 conference was held in Orlando, FL from December 7-10, 2019. Researchers from the Bing Center contributed an oral presentation (Guang Yang), and three posters (Jorge Castill, and Xia Liu).  

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IWMF Adds Three Members to Scientific Advisory Committee

IWMF Adds Three Members to Scientific Advisory Committee

The IWMF is proud to welcome three new members to its Scientific Advisory Committee (SAC) chaired by Dr. Stephen Ansell of the Mayo Clinic and Dr. Steven Treon of the Dana-Farber Cancer Institute. The new members, Dr. Zachary Hunter from Dana-Farber, Boston, USA, Dr. Christian Buske from Ulm, Germany, and Dr. Monique Minnema of The Netherlands, were invited to participate because of their expertise in specific research areas identified by the IWMF-LLS Strategic Research Roadmap for WM.

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Dr. Edward Laane - Running for WM! (Part-2)

Dr. Edward Laane - Running for WM! (Part-2)

On November3, 2019, Dr. Edward Laane ran the Osaka Yodo River Half Marathon, to raise money for Waldenstrom's research. His pure running time was 2.26.07 with his official time listed at 2.31.0. As Dr. Laane recalls, "The run was difficult. It was sunny, and a little bit hot. The first part, 6.5 miles was a little easier. My time was approximately 1h 10 min, but the second part was very difficult. But I was thinking about the patients who have gone through so much treatment and this gave me more strength to finish.

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New Approaches to treating Waldenstrom's Macroglobulinemia

New Approaches to treating Waldenstrom's Macroglobulinemia

At the 2019 Lymphoma & Myeloma Congress, Steven Treon, MD, PhD, FACP, FRCP, Harvard University, Dana-Farber Cancer Institute, Bing Center for Waldenström Macroglobulinemia, Boston, Massachusetts, provided an update on the latest research in the treatment of Waldenström Macroglobulinemia.

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Dr. Edward Laane - Running for WM!

Dr. Edward Laane - Running for WM!

Dr. Edward Laane is running in the Osaka Yodo River Citizens Marathon to raise money for Waldenstrom's research!

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IMW-17 Young Investigator Awards

IMW-17 Young Investigator Awards

Congratulations to the following Bing Center researchers for their Young Investigator Awards at the 17th International Workshop on Multiple Myeloma!

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